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Alachua County is best known as the home of the University of Florida, and much of its economy revolves around the university. The Alachua area appears to have been the first area occupied by the immigrant Oconees, the original Seminoles, about 1740. Their first town was situated on or near the old Alachua plain, now called Payne's Prairie in homage to "King" Payne, chief of the Alachua settlements upon his death in 1812. The meaning of Alachua is suggested by a passage in the journal of Lieutenant Diego Peña when he names several watering places that all possess the terminator "chua", which suggests that chua is the Timucuan name for sinkhole. This inference is not inconsistent with the general opinion of residents of the county, that the name Alachua means sinkhole. (Wikipedia).